DEVELOPING COUNTRIES

Professor Xiaobing Fu, MD

Resume

Professor Xiaobing Fu, M.D., the director of the Wound Healing and Cell Biology Laboratory, the Key Research Laboratory of the Wound Repair and the Vice Director of the Burn Institute in 304th Hospital, Trauma Center of Postgraduate Medical College. He was born on Aug. 14, 1960 and graduated from the Third Military Medical University in 1988 with the master degree and the University of Madrid in 1993 with the doctor degree.

He has been engaged in trauma research, especially in wound healing research for twenty years. He has made great contributions on the basic research on growth factors and wound healing, physiological mechanisms of wound healing, “uncontrolled wound healing”, such as clinical trial about the growth factors and their application in accelerating acute or chronic wound healing, growth factors and internal organ repair (including gut, kidney, liver and lung, etc), the mechanisms of chronic ulcer and scar development and so on. His works were supported in part by the National Basic Science and Development Programme (973 Programme), National High-Technique Programme (863 Programme), Grant for National Distinguished Young Scientists and Grant for National Natural Science Foundation of China.

He has published more than 250 scientific papers, including the Lancet (1998, 2001), and 4 books as the editor in chief, and won the ten international and national prizes of Sci-Tech progress from 1989 to 2002. He was the member of the Scientific Committee of the Third Joint Meeting of the European Tissue Repair Society and the Wound Healing Society held in Bordeaux in1999, the Scientific Committee Member of the First World Healing Congress held in Melbourne in 2000 and the Vice Chairman of Trauma and Burn Section of the International Conference on Life Science and Clinical Medicine in 2000.

Now, he is the President of the Chinese Tissue Repair Society and the member of the National Natural Science Foundation of China. He is also the Editorial Board Members of the Wound Repair and Regeneration (The International Journal of Tissue Repair and Regeneration) and the Science in China (Series C), etc.

Curriculm Vitae

Name: Xiaobing Fu, MD
Director, Professor
Address: Wound Healing Unit, Burns Institute, 304th Hospital, Trauma Center of Postgraduate Medical College, 51 Fu Cheng Road, Beijing 100037, P.R. China

Fax: 0086 10 68480755
0086 10 88416390
Tel: 0086 10 66867396
0086 10 68438604
Email: Fuxb@cgw.net.cn; fuxiaobing@vip.sina.com

Education

1991.04 – 1993.12: Department of Pathology, University Hospital Ramon Y Cajal, University Alcala de Henares, Madrid, Spain, MD

1985.09 – 1988.07: The Third Military Medical University, Chongqing, Postgraduate student, MD

1988.03 – 1988.07: Training Department of English for Students Preparing to Study Abroard, Sichuan Institute of Foreign Languages, Chongqing,

1984.03 – 1984.07: Pathological Department, The Third Military Medical University, Chongqing

1978.09 – 1983.07: The Third Military Medical University, Chongqing, Graduate Student, B.Sc

Teaching appointments and research work

1993.12 – Present: Wound Healing Unit, Burns Institute, 304th Hospital, Trauma Centre of Postgraduate Medical College, Beijing
Associate Professor, Professor, Director.

1991.04 – 1993.12: Department of Pathology, University Hospital Ramon Y Cajal, University Alcala de Henares, Madrid, Spain
Research Fellow

1988.08 – 1991.04: Wound Healing Unit, 304th Hospital, Trauma Centre of Postgraduate Medical College, Beijing
Research Assistant, Visiting Doctor

1983.08 – 1985.08: Research Institute of Surgery, The Third Military Medical University, Chongqing
Doctor

Memberships and Offices in Professional Societies

Editorial Board Member of the International Journal Of Wound Repair and Regeneration (2003-)

Editorial Board Member of Sciences in China (Series C) (2003-)

President of Chinese Tissue Repair Society (CTRS) (1999-)
Vice President of Trauma and Burn Forum, 2000 years International Meeting of Life Science and Clinical Medicine, Organised by Chinese Academy of Engineer (CAE)
Member of Scientific Committee of the First World Healing Conference in Melbourne (2000)

Scientific Committee Member of the Second Joint Meeting Of Wound Healing Society (WHS) and European Tissue Repair Society (ETRS) in Bordeaux in 1999

Vice-President of First joint meeting of the Chinese Tissue Repair Society and the European Tissue Repair Society, Xi’an, China, 1996

Member of the European Tissue Repair Society (1993-)

Committee member of the Chinese Trauma Society (1996-)

Vice-President of Trauma Society of PLA (1996-)

Member of the Spanish Society for Surgical Research (1993-)

Invited Participant to International Meetings

New genetic drugs and their use in wound repair and regeneration. Medicine in the 21st Century. The Second Sino-US Symposium. Shanghai, China, Oct. 26-28 2002

Advances in wound healing research in China.
2000 years International Meeting of Life Science and Clinical Medicine, Beijing, China, April 19 to 23, 2000

Alteration of endogenous bFGF and TGF_in lung induced by intestinal ischemia and reperfusion insult.
Gene expression of c-fos and c-jun in lung induced by intestinal ischemia and reperfusion and their effects on bFGF gene activation.
3rd Joint Meeting of the European Tissue Repair Society and the Wound Healing Society, Bordeaux, France, August 24 to 28, 1999

8th Annual Meeting of the European Tissue Repair Society, Copenhagen, Denmark, August 22 to 25, 1998

A preliminary epidemiological study of chronic ulcers in China.
The distribution of apoptosis in diabetic ulcers.
7th Annual Meeting of the European Tissue Repair Society, Koln, Germany, August 23-26, 1997

Tissue Repair Engineering Innovation in Wound Healing Gene Therapy, Freiberg, Germany, August 20 to 22, 1997

Study on abnormal proteins in serum in patients with chronic ulcers.
PAN/Asian European Tissue Repair Society Wound Healing Meeting, Phuket, Thailand, October 28-31, 1997

Basic Fibroblast growth factor (bFGF) reduces gut and liver ischemia and reperfusion injuries.
First Joint Meeting of the Chinese Tissue Repair Society and the European Tissue Repair Society, Xi’an, China, September 22-27, 1996

The Second Joint Meeting of the Wound Healing Society and the European Tissue Repair Society, Boston, USA, May 15-17, 1996

Clinical results of trials with recombinant basic fibroblast growth factor (bFGF) on 485 cases.
5th Annual Meeting of the European Tissue Repair Society, Padova, Italy, August 30 to September2, 1995
Immunohistochemical localization of basic fibroblast growth factor (bFGF) in normal and ischemia and reperfused rat kidney

4th Annual Meeting of the European Tissue Repair Society, Oxford, UK, August 25 to 28, 1994

Basic fibroblast growth factor (bFGF) immunoreactivity in developing granulation tissue.
The first Joint Meeting of the Wound Healing Society and the European Tissue Repair Society, Amsterdam, The Netherlands, August 22 to 25,1993

Effects of fibroblast growth factor in ischemic and reperfused rat skeletal muscle 6th World Congress on Intensive and Critical Care Medicine, Madrid, Spain, June 14 to 18, 1993

Main Publications (in English)

1. Fu Xiaobing, et al. Healing of chronic cutaneous wounds by topical treatment with basic fibroblast growth factor. Chin Med J 2002; 115(3): 331-335
2. Fu Xiaobing, et al. Comparative study of fibronectin gene expression in tissues from hypertrophic scars and diabetic foot ulcers. Chin Med Sci J 2002; 17(2): 90-94
3. Fu Xiaobing, et al. Dedifferentiation of epidermal cells to stem cells in vivo. The Lancert 2001; 358:1067-1068
4. Fu Xiaobing, et al. Advances in wound healing research in China: From antiquity to modernity. Wound Rep Reg 2001; 9: 2-10
5. Fu Xiaobing, et al. Expression of oncoproteins c-fos and c-jun in hypertrophic scars and chronic dermal ulcers and their regulation of basic fibroblast growth factor. Chin Med J 2001; 114(8): 852-856
6. Fu Xiaobing, et al. Recombinant bovine basic fibroblast growth factor accelerates wound healing in patients with burns, donor sites and chronic dermal ulcers. Chin Med J 2000; 113(4): 367-371
7. Fu Xiaobing, et al. Effect of intestinal ischemia-reperfusion on expressions of endogenous basic fibroblast growth factor and transforming growth factor in lung and its relation with lung repair. World J Gastroentero 2000; 6(3): 353-355
8. Fu Xiaobing, et al. Randomized placebo controlled trial use of tropical recombinant bovine basic fibroblast growth factor for second degree burns. The Lancet 1998; 352(21): 1661-1664
9. Fu Xiaobing, et al. Ischemia and reperfusion impair the gene expression of endogenous basic fibroblast growth factor in rat skeletal muscles. J Surg Res 1998;80: 88-93
10. Fu Xiaobing, et al. Epidemiological study of chronic dermal ulcers in China. Wound Rep Reg 1998; 6(1): 21-27
11. Fu Xiaobing, et al. The effects of fibroblast growth factor on ischemic kidney, liver and gut injury. Chin Med J 1998; 14(5): 398-403
12. Fu Xiaobing, et al. bFGF reduces the gut and liver morphologic and functional injury after ischemia and reperfusion. J Trauma 1997; 42(6): 1080-1085
13. Fu Xiaobing, et al. Beijing wound healing unit and its rule in management of wounds. European Tissue Repair Society Bulletin 1997; 4(1): 14-16
14. Fu Xiaobing. Wound Healing Research in China. Wound Rep Reg 1995; 4(4): 237-238
15. Fu Xiaobing, et al. Acidic fibroblast growth factor (aFGF) reduces renal morphologic and functional injuries caused by ischemia and reperfusion. Wound Rep Reg 1996; 5(4): 297-303
16. Fu Xiaobing, et al. Multiple organ injuries and failures caused by shock and reperfusion after gunshot wounds. J Trauma 1996; 40(3): S135-S139
17. Fu Xiaobing, et al. The in vivo effects of tumor necrosis factor on incised wound and gunshot wound healing. J Trauma 1996; 40(3): S140-S143
18. Fu Xiaobing, et al. Acidic fibroblast growth factor (aFGF) reduces postischemic renal injury in rats. J Trauma (China) 1996; 12(3): 11-16
19. Fu Xiaobing, et al. Effects of basic fibroblast growth factor on ischemic gut and liver injuries. Chin Natl J Gastroenterol 1996; 2(3): 139-140
20. Fu Xiaobing. Chinese Tissue Repair Society. European Tissue Repair Society Bulletin 1995; 2(4): 112-113
21. Fu Xiaobing, et al. Ischemia and reperfusion reduce the endogenous basic fibroblast growth factor (bFGF) in rat skeletal muscles. An immunohistochemical study. Wound Rep Reg 1996; 4(3): 381-385
22. Fu Xiaobing, et al. Acidic fibroblast growth factor reduces rat skeletal muscle damage caused by ischemia and reperfusion. Chin Med J 1995; 108 (3): 209-214
23. Fu Xiaobing, et al. Ischemia and reperfusion reduces the endogenous basic fibroblast growth factor in rat skeletal muscles. Chin Med J 1995; 108(9): 699-703
24. Fu Xiaobing, et al. Acidic fibroblast growth factor reduces renal morphological and functional indicators of injury caused by ischemia and reperfusion. Wound Rep Reg 1996; 4(2): 297-3033
25. Fu Xiaobing, et al. Basic fibroblast growth factor (bFGF) immunoreactivity in developing granulation tissue. J Trauma (China) 1995; 11(6): 87-91
26. Fu Xiaobing, et al. The spectacles facilitating debridement: A report of 300 cases. Chin Med J 1991; 104(8): 693-696
27. Fu Xiaobing, et al. Acidic fibroblast growth factor (aFGF) reduces renal morphological and functional injuries caused by ischemia and reperfusion. Jap J Surg 1994; 94: S76
28. Fu Xiaobing, et al. Multiple organ injury after abdominal high energy wounding in animals and the protective effect of antioxidants. Chin Med Sci J 1992; 7(2): 86-91
29. Fu Xiaobing. Management of casualties in Gulf War. Brit J Surg 1993; 80(9): 691
30. Fu Xiaobing, et al. Special spectacles facilitating debridemant: a report of their use in 300 cases. Injury 1992: 23 (1): 64-66
31. Cheng Biao, Fu Xiaobing, et al. The different expressions epidermal growth factor receptor and related phosphorylation proteins in hypertrophic scars and normal skin. Chin J Med 2002; 115(10): 1525-1528 (Fu Xiaobing: Correspondence author)
32. Li Jianfu, Fu Xiaobing, et al. The interaction between epidermal growth factor and matrix metalloproteinase induces the development of sweat glands in human fetal skin. J Surg Res 2002; 106:258-263 (Fu Xiaobing: Correspondence author)
33. Yang Yinhui, Fu Xiaobing(4), et al. Long-term mortality of ultrasound structure in patients with venous leg ulcers-healed from one week to twenty years. Chin Med J 2002; 115(12): 1819-1823
34. Chen Wei, Fu Xiaobing, et al. Review of current progress in the structure and function of Smad proteins. Chin Med J 2002; 115 (3):446-450
35. Sun Xiaoqing, Fu Xiaobing, et al. Relationship between plasma D (-)-lactate and Intestinal damage after severe injuries in rats. World J Gastroentero 2001; 7(4): 555-558
36. Gu Xiaoman, Fu Xiaobing, et al. Expression characteristics of c-fos, c-myc and bFGF in early burn tissue. Chin Med J 2001; 81 (9): 925-928
37. Yang Yinhui, Fu Xiaobing, et al. bFGF and TGF_expression in rat kidneys after ischemic reperfusional gut injury and its relationship with tissue repair. World J Gastroentero 2000; 6(1): 147-149
38. Gu Xiaoman, Fu Xiaobing, et al. MRNA and protein expression of transcription factor c-fos in burned rats and their effects on wound healing. Chin J Trauma 2000; 3(3): 141-145

Books

1. Fu Xiaobing, Editor in Chief. Growth Factor and Wound healing. Military Medical Press, 1991
2. Fu Xiaobing, Editor in Chief. Basic Wound healing, Military Medical Press, 1997
3. Fu Xiaobing, Editor in Chief. Text Book: Modern Wound Healing, Military Medical Press, 1999
4. Fu Xiaobing, Editor in Chief. Modern High-Technology and Tissue Repair and Regeneration, Military Medical Press, 2002

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